We’re proud to announce that Nevada Center for Biomedical Research will be well represented at the 12th International IACFS/ME Research and Clinical Conference: Emerging Science and Clinical Care in Ft. Lauderdale, FL, from October 27-30, 2016. Dr. Vincent Lombardi, NVCBR Research Director, Dr. Kenny De Meirleir, NVCBR Medical Director, and Annette Whittemore, NVCBR CEO, will [...]
Failure of gut-associated pDCs to express membrane bound APRIL and BAFF prevents their ability to promote low-affinity IgA expression in ME/CFS
Authors: Vincent C Lombardi, Svetlana F Khaiboullina, Kenny L De Meirleir, Tanja Mijatovic, Jan Hulstaer Link: http://www.jimmunol.org/content/196/1_Supplement/137.4 Publication: The Journal of Immunology (2016) Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous illness characterized by a number of comorbid conditions; gastrointestinal (GI) dysregulation make up one subgroup of this disease. IgA is the most abundant antibody isotype found in mucosal secretions including [...]
Decreased Numbers of CD57+CD3− Cells Identify Potential Innate Immune Differences in Patients with Autism Spectrum Disorder
Authors: Siniscalco D, Mijatovic T, Bosmans E, Cirillo A, Kruzliak P, Lombardi VC, DE Meirleir K, Antonucci N Link: https://www.ncbi.nlm.nih.gov Publication: in vivo (2016) Background. Autism spectrum disorders (ASD) are complex, and severe heterogeneous neurodevelopmental pathologies with accepted but complex immune system abnormalities. Additional knowledge regarding potential immune dysfunctions may provide a greater understanding of [...]
Dr. Lombardi presented at the 2016 American Association of Immunologists annual meeting in Seattle, Washington.LEARN MORE
Transcriptional Analysis of Blood Lymphocytes and Skin Fibroblasts, Keratinocytes, and Endothelial Cells as a Potential Biomarker for Alzheimer’s Disease.
Authors: Mukhamedyarov MA, Rizvanov AA, Yakupov EZ, Zefirov AL, Kiyasov AP, Reis HJ, Teixeira AL, Vieira LB, Lima LM, Salafutdinov II, Petukhova EO, Khaiboullina SF, Schlauch KA, Lombardi VC, Palotás A. Link: https://www.ncbi.nlm.nih.gov/pubmed/27589530 Publication: J Alzheimers Dis. 2016 Sep 2. [Epub ahead of print] Alzheimer's disease (AD) is a devastating and progressive form of dementia [...]
Hantavirus Infection Suppresses Thrombospondin-1 Expression in Cultured Endothelial Cells in a Strain-Specific Manner.
Authors: Khaiboullina SF, Morzunov SP, St Jeor SC, Rizvanov AA, Lombardi VC. Link: https://www.ncbi.nlm.nih.gov/pubmed/27486439 Publication: Front Microbiol. 2016 Jul 19;7:1077. doi: 10.3389/fmicb.2016.01077. eCollection 2016. Hantavirus infection is associated with two frequently fatal diseases in humans: Hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). The pathogenesis of hantavirus infection is complex and not fully [...]